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Critical Reviews in Oncology / Hematology
Volume 74, Issue 2
, Pages 73-78
, May 2010
The upgraded role of HER3 and HER4 receptors in breast cancer
References
- . EGF receptor ligands. Exp Cell Res. 2003;284:2–13
- . Oncogenic growth factor receptors: implications for signal transduction therapy. Semin Cancer Biol. 2004;14:262–270
- . Tyrosine kinases as targets for cancer therapy. N Engl J Med. 2005;353:172–187
- . Breast cancer: The upgraded role of HER-3 and HER-4. Int J Biochem Cell Biol. 2007;39:851–856
- . Identification of c-erbB-3 binding sites for phosphatidylinositol 3′-kinase and SHC using an EGF receptor/c-erbB-3 chimera. EMBO J. 1994;13:2831–2841
- . ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol Cell Biol. 1994;14:3550–3558
- . A new mutational AKTivation in the PI3K pathway. Cancer Cell. 2007;12:104–107
- . ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer. J Mammary Gland Biol Neoplasia. 2008;13:215–223
- . The deaf and the dumb: the biology of ErbB-2 and ErbB-3. Exp Cell Res. 2003;284:54–65
- . The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc Natl Acad Sci USA. 2003;100:8933–8938
- . Expression of c-erbB3 protein in primary breast carcinomas. Br J Cancer. 1998;78:1385–1390
- . Prognostic value of ERBB family mRNA expression in breast carcinomas. Int J Cancer. 2003;106:758–765
- . Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer. J Pathol. 2003;200:290–297
- Cytogenetic analysis of HER1/EGFR, HER2, HER3, and HER4 in 278 breast cancer patients. Breast Cancer Res. 2008;10:R2;[Epub 2008 Jan 8]
- Expression of the ERBB3 gene product in breast cancer. Br J Cancer. 1992;66:1116–1121
- C-erbB-3 and c-erbB-2 protein expression in node-negative breast carcinoma. An immunocytochemical study. Eur J Cancer. 1994;30A:16–22
- . C-erbB-3 protein expression in human breast cancer: comparison with other tumour variables and survival. Histopathology. 1994;25:247–252
- C-erbB-3 in human breast carcinoma: expression and relation to prognosis and established prognostic indicators. Br J Cancer. 1996;74:229–233
- . Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay. Clin Cancer Res. 2000;6:4217–4225
- Correlated expression of erbB-3 with hormone receptor expression and favourable clinical outcome in invasive ductal carcinomas of the breast. Am J Clin Pathol. 2007;128:1041–1049
- Evaluation of the prognostic and predictive value of HER family mRNA expression in high-risk early breast cancer. Br J Cancer. 2008;99:1775–1785[Epub 2008 Nov 4]
- . A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4. Cancer Res. 2001;61:4467–4473
- . c-erbB-3: a nuclear protein in mammary epithelial cells. J Cell Biol. 2002;157:929–939
- . Downregulation of erbB3 abrogates erbB2-mediated tamoxifen resistance in breast cancer cells. Int J Cancer. 2007;120:1874–1882
- . Targeted therapies for the treatment of breast cancer in the post-trastuzumab era. Oncologist. 2008;13:373–381
- Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3. Nature. 2007;445:437–441
- . Transphosphorylation of kinase-dead HER3 and breast cancer progression: a new standpoint or an old concept revisited?. Breast Cancer Res. 2007;9:111
- . Targeting HER proteins in cancer therapy and the role of the non-target HER3. Br J Cancer. 2007;97:453–457
- . The efficacy of Herceptin therapies is influenced by the expression of other erbB receptors, their ligands and the activation of downstream signalling proteins. Br J Cancer. 2004;91:1190–1194
- . Trastuzumab-induced HER reprogramming in “resistant” breast carcinoma cells. Cancer Res. 2009;69:2191–2194[Epub 2009 Mar 10]
- Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells. Mol Cell Biol. 2001;21:4265–4275
- The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells. Cancer Res. 2006;66:6412–6420
- . Absence of HER-4 expression predicts recurrence of ductal carcinoma in situ of the breast. Clin Cancer Res. 2005;11:2163–2168
- . A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis. J Biol Chem. 2000;275:8641–8649
- . Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4. J Biol Chem. 2000;275:10379–10387
- . Gamma-secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science. 2001;294:2179–2181
- . HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer. J Mammary Gland Biol Neoplasia. 2008;13:247–258
- Coregulation of estrogen receptor by estrogen-inducible ERBB4/HER4 establishes a growth promoting autocrine signal in breast cancer. Cancer Res. 2006;66:7991–7998
- c-erbB-3 and c-erbB-4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer. Oncogene. 1998;17:1949–1957
- . Ribozyme-mediated down-regulation of ErbB-4 in estrogen receptor-positive breast cancer cells inhibits proliferation both in vitro and in vivo. Cancer Res. 1999;59:5315–5322
- C-erbB-4 protein expression in human breast cancer. Br J Cancer. 2000;82:1163–1170
- EGFR family expression in breast carcinomas. C-erbB-2 and c-erbB-4 receptors have different effects on survival. J Pathol. 2002;196:17–25
- Gene copy numbers of HER family in breast cancer. J Cancer Res Clin Oncol. 2008;134:271–279
- PTK (protein tyrosine kinase)-6 and HER2 and 4, but not HER1 and 3 predict long-term survival in breast carcinomas. Br J Cancer. 2007;96:801–807
- Cleavable ErbB4 isoform in estrogen receptor-regulated growth of breast cancer cells. Cancer Res. 2005;65:1384–1393
- . The HER4/4ICD estrogen receptor coactivator and BH3-only protein is an effector of tamoxifen-induced apoptosis. Cancer Res. 2008;68:6387–6395
- . The epidermal growth factor receptor family in breast cancer. OncoTargets Ther. 2008;1:5–19
- . Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types. J Pathol. 1998;185:236–245
- . Expression of epidermal growth factor receptor mRNA and protein in primary breast carcinomas. Breast Cancer Res Treat. 1999;53:167–176
PII: S1040-8428(09)00102-4
doi: 10.1016/j.critrevonc.2009.04.011
© 2009 Elsevier Ireland Ltd. All rights reserved.
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Critical Reviews in Oncology / Hematology
Volume 74, Issue 2
, Pages 73-78
, May 2010
