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Critical Reviews in Oncology / Hematology
Volume 46, Issue 3
, Pages 221-234
, June 2003
The role of pineal gland in breast cancer development
References
- . Cancer burden in the year 2000. The global picture. Eur. J. Cancer. 2000;37:S4–S66
-
.
Why the incidence of cancer is increasing: the role of ‘light pollution’.
Med. Hypoth. 1990;33:75–78
-
.
Circadian disruption and breast cancer.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 511–517
- . Light in the built environment: potential role of circadian disruption in endocrine disruption and breast cancer. Cancer Causes Control. 2001;12:279–287
-
.
Melatonin and the mammalian pineal gland. London: Chapman and Hall; 1995;
-
.
Circadian rhythms: new functions for old clock genes?.
Trends Gene. 2000;16:135–142
- Senescence, sleep, and circadian rhythms. Ageing Res. Rev. 2002;1:559–604
-
.
The significance of circadian organization for longevity in the golden hamster.
J. Biol. Rhyth. 1998;13:430–436
- . The Tromso Heart Study. Acta Med. Scand. 1976;200:107–118
- . Day and night work: changes in cholesterol, uric acid, glucose and potassium in serum and circadian patterns of urinary catecholamine excretion. Acta Med. Scand. 1976;200:47–53
- . Prevalence of risk factors for coronary artery disease among day and shift workers. Scand. J. Work Environ. Health. 1988;14:317–321
- Prospective study of shift work and risk of coronary heart disease in women. Circulation. 1995;92:3178–3182
- . Job stress and mental health among permanent night workers. J. Occup. Health. 2001;43:301–306
-
Ulceroprotective effect of melatonin during artificial simulation of desynchronization in rats.
Vestnik. Russ. Acad. Med. Sci. 2000;8:21–25
- . Die Lebesdauer von Fliegen inter dem Einfluss von Zeitverschiebungen. Naturwissenschaften. 1971;58:574
-
.
The effect of different light regimes on adult life span in Drosophila melanogaster is partly mediated through reproductive output.
J. Biol. Rhyth. 2000;15:380–392
- . Light and reproduction in the rat. Effect of early lighting on response measured in adult females. Biol. Reprod. 1973;8:473–480
- . Light and reproduction in the rat: effects of photoperiod length on albino rats from two different breeders. Biol. Reprod. 1970;2:255–261
- . The effect of constant light on the estrus cycle and behavior of the female rat. Physiol. Behav. 1970;5:421–425
- . Endocrine changes in two strains of mice exposed to constant illumination. Endocrinology. 1970;86:914–917
-
.
Trends in photophysiologic concepts.
Ann. N.Y. Acad. Sci. 1964;117:88–104
-
Smirnova IO. Experimental Bases of Treatment of Mastopathy with Iodine Microdoses. PhD Thesis. All-Union Cancer Center, Moscow, 1966.
-
.
Follicular cysts of the ovary and dyshormonal tumors. Leningrad: Meditsina; 1966;
-
.
Experimental models of endocrine gynecological diseases. Moscow: Meditsina; 1976;
- . Effect of continuous light on the incidence of 9,10-dimethyl-1,2-benzanthracene induced mammary tumors in female Holtzman rats. Cancer Lett. 1982;16:313–317
-
.
Light deprivation, electromagnetic fields and mammary carcinogenesis.
Adv. Pineal Res. 1994;7:229–234
- . The relationship between electromagnetic field and light exposure to melatonin and breast cancer risk: a review of the relevant literature. J. Pineal Res. 1999;26:65–100
- . Circadian concepts in normal and neoplastic breast. Chronobiol. Int. 2002;19:221–235
-
.
Pineal melatonin: cell biology of its synthesis and of its physiological interactions.
Endocrin. Rev. 1991;12:151–180
-
.
Potential biological consequences of excessive light exposure: melatonin suppression, DNA damage, cancer and neurodegenerative diseases.
Neuroendocrinol. Lett. 2002;23(Suppl 2):9–13
- . Residental magnetic fields, light-at-night, and nocturnal urinary 6-sulfatoxymelatonin concentration in women. Am. J. Epidemiol. 2001;154:591–600
- . Examination of the melatonin hypothesis in women exposed at night to EMF or bright light. Environ. Health Perspect. 2001;109:501–507
-
.
Ocular input for human melatonin regulation: relevance to breast cancer.
Neuroendocrinol. Lett. 2002;23(Suppl 2):17–22
-
Yu HS, Reiter RJ, editors. Melatonin. Biosynthesis, physiological effects, and clinical applications. Boca Raton, FL: CRC Press, 1993.
- . Night shift work, light at night, and risk of breast cancer. J. Natl. Cancer Inst. 2001;93:1557–1562
- Rotating night shifts and risk of breast cancer in women participating in the nurses’ health study. J. Natl. Cancer Inst. 2001;93:1563–1568
-
.
Incidence of cancer among Finnish airline cabin attendants, 1967–92.
Br. Med. J. 1995;311:649–652
- . Incidence of breast cancer in Norwegian female radio and telegraph operators. Cancer Causes Control. 1996;7:197–204
-
.
Increased breast cancer risk among women who work predominantly at night.
Ann. Epidemiol. 2001;12:74–77
- . Risk of breast cancer in female flight attendants: a population-based study (Iceland). Cancer Cause Control. 2001;12:95–101
- . Role of pineal gland in aetiology and treatment of breast cancer. Lancet. 1978;2:814–816
- . The melatonin hypothesis: electric power and breast cancer. Environ. Health Perspect. 1996;104(Suppl 1):135–140
-
.
In:
Everitt AV, Burgess JA editor. Aging in the hypothalamic–hypophyseal–ovarian axis in the rat. Springfield: Charles C Tomas; 1976;p. 376–392
-
.
Blastomogenesis in persistent-estrus rats.
Vopr. Onkol. 1971;8:67–75
-
.
Carcinogenesis and aging. 2. Boca Raton: CRC Press; 1987;
- . Hypothalamic mechanisms of ageing and of specific age pathology-I. Sensitivity threshold of hypothalamo–pituitary complex to homeostatic stimuli in the reproductive system. Exp. Gerontol. 1979;14:161–174
-
.
Development, aging and disease.
A new rationale for an intervention strategy. Chur: Harwood Academic; 1994;
- . Gonadotropin secretion during aging in women: review article. Exp. Gerontol. 1996;30:369–381
-
Effect of light regime and melatonin on the development of spontaneous mammary tumors in HER-2/neu transgenic mice is related to a downregulation of HER-2/neu gene expression.
Neuroendocr. Lett. 2001;22:439–445
-
.
Effects of melatonin and constant light on the development of spontaneous endometrial carcinomas in aging BDII/Han rats appear to be exerted by modulation of maturation of the reproductive system.
Z. Gerontol. Geriatr. 1999;32(Suppl 2):II/5
- . Light contamination during the dark phase in photoperiodically controlled animal rooms: effect on tumor growth and metabolism in rats. Lab. Anim. Sci. 1997;47:511–517
-
.
Effect of hypothalamo-pituitary lesions induced by constant illumination on development of induced mammary tumors in rats.
Vopr. Eksp. Onkol. (Kiev). 1965;1:87–93
-
.
Environmental light and DMBA-induced rat mammary tumours.
Br. J. Surg. 1968;55:71–76
- . Influence of environmental light and melatonin upon mammary tumour induction. Br. J. Surg. 1969;56:764–766
-
.
Influence of light and 9,10-dimethylbenz(a) anthracene on rat ovarian steroidogenesis: neutral steroids.
Biochem. J. 1968;110:29p–30p
-
.
Influence of light and 9,10-dimethylbenz(a)-anthracene on rat ovarian steroidogenesis: phenolic steroids.
Biochem. J. 1968;110:28p–29p
-
.
Effect of melatonin on the mammary gland morphology, DNA synthesis, hormone profiles and incidence of mammary cancer in rats.
In:
Gupta D, Attanasio A, Reiter RJ editor. The pineal gland and cancer. London: Brain Research Promotion; 1988;p. 210–219
- . The effect of infection, hormonal environment, and genetic constitution on mammary tumor induction in rats by 7,12-dimethylbenz(a)anthracene. Cancer Res. 1966;26:2368–2373
- . Effect of melatonin on mammary carcinogenesis in intact and pinealectomized rats in varying photoperiods. Cancer Res. 1984;44:3403–3407
- . Effect of varying photoperiods on mammary morphology, DNA synthesis and hormonal profile in female rats. J. Natl. Cancer Inst. 1984;72:1411–1416
- . Effect of constant light on DMA mammary tumorigenesis in rats. Cancer Lett. 2000;148:121–126
- . Mammary gland neoplasia in long-term rodent studies. Environ. Health Perspect. 1996;104:938–967
-
.
An overview on the neuroendocrine regulation of experimental tumor growth by melatonin and its analogues and the therapeutic use of melatonin in oncology.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 309–342
- . The effect of short intermittent light exposures on the melatonin circadian rhythm and NMU-induced breast cancer in female F344/N rats. Toxicol. Pathol. 2001;29:126–136
- . The tumor promoting effect of constant light exposure on diethylnitrosamine-induced hepatocarcinogenesis in rats. Life Sci. 1999;64:2523–2534
- . Effect of light/dark regimen on N-nitrosoethylurea-induced transplacental carcinogenesis in rats. Cancer Lett. 2001;163:51–57
-
.
Effect of dark adaptation on carcinogenesis and efficacy of treatment DMBA-induced mammary tumor.
Izvestia Akad. Nauk. Kazakh. SSR Ser. Biol. 1979;4:79–82
-
Kuralasov AK. Experimental Bases for Application of Artificial Photoregimen for Breast Cancer Treatment in Kazakhstan. Diss Doctor Med Sci. Moscow: All-Union Cancer Center, 1990.
-
.
Oncostatic signaling by the pineal gland and melatoninin the control of breast cancer.
In:
Gupta D, Attanasio A, Reiter RJ editor. The pineal gland and cancer. London: Brain Research Promotion; 1988;p. 221–232
-
.
The pineal: an oncostatic gland.
In:
Reiter RJ editors. The pineal gland. New York: Raven Press; 1984;p. 253–284
-
.
Influence of pineal function on the initiation and growth of hormone-dependent breast tumors. Possible mechanisms.
In:
Gupta D, Attanasio A, Reiter RJ editor. The pineal gland and cancer. London: Brain Research Promotion; 1988;p. 221–232
-
.
Profound bilateral blindness and the incidence of breast cancer.
Epidemiology. 1991;2:108–210
- . Reduced cancer incidence among the blind. Epidemiology. 1998;9:490–494
- . Visual impairment and cancer: a population-based cohort study in Finland. Cancer Causes Control. 1999;10:13–20
- . Inverse association between breast cancer incidence and degree of visual impairment in Finland. Br. J. Cancer. 1999;80:1459–1460
- . Melatonin and mammary pathological growth. Front. Neuroendocrinol. 2000;21:133–170
-
.
In vitro effects of melatonin on tumor cells.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 221–239
- . Effects of melatonin on cancer: studies on MCF-7 human breast cancer cells in culture. J. Neural. Transm. (Suppl). 1986;21:433–449
-
.
Is melatonin really an in vitro inhibitor of human breast cancer cell proliferation in vitro.
Cell Dev. Biol. 1992;28A:583–584
-
.
Melatonin modulation of estrogen receptor expression in MCF-7 human breast cells.
Int. J. Oncol. 1993;3:687–694
- . Melatonin blocks the stimulatory effects of prolactin on human breast cancer cell growth in culture. Br. J. Cancer. 1995;72:1435–1440
- . Circadian rhythms of basic fibroblast growth factor (bFGF), epidermal growth factor (EGF), insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), cortisol, and melatonin in women with breast cancer. Chronobiol. Int. 2001;18:709–727
- . Correlation of anti-tumor activity of pineal and hypothalamic extracts, melatonin and sygetin in mouse transplantable mammary tumor. Vopr. Onkol. 1973;10:99–101
-
.
Effect of pinealectomy and melatonin on mammary tumor growth in Sprague–Dawley rats under different conditions of lighting.
J. Neural. Trans. 1980;47:121–130
- . Inhibitory effects of the pineal hormone melatonin and underfeeding during the promotion phase of 7,12-dimethylbenz[a]-anthracene-(DMBA)-induced mammary tumorigenesis. J. Neural. Transm. 1986;67:125–138
- . Influence of chronic melatonin on 9,10-dimethyl-1,2-benzanthrazene-induced mammary tumors in female Holtzman rats exposed to continuous light. Oncology. 1987;44:64–66
- . Suppressive effect by melatonin on different phases of 9,10-dimethyl-1,2-benzathracene (DMBA)-induced rat mammary gland carcinogenesis. Anticancer Drugs. 1991;2:297–303
- . Melatonin inhibition and pinealectomy enhancement of 7,12-dimethylbenz[a]anthracene-induced mammary tumors in the rat. Cancer Res. 1981;41:4432–4436
- . Host factors affecting the growth of carcinogen-induced rats mammary carcinomas: a review and tribute to Charles Benton Huggins. Cancer Res. 1985;45:3415–3443
- Pineal melatonin inhibition of tumor promotion in the N-nitroso-N-methylurea model of mammary carcinogenesis: potential involvement of antiestrogenic mechanisms in vivo. J. Cancer Res. Clin. Oncol. 1991;117:526–532
- . Chemoprevention by melatonin and combined melatonin-tamoxifen therapy of second generation nitroso-methylurea-induced mammary tumour in rats. Eur. J. Cancer Prev. 1995;4:497–500
- . Combination of melatonin and tamoxifen as a chemoprophylaxis against N-nitroso-N-methylurea-induced rat mammary tumors. Cancer Lett. 1997;111:59–66
-
Effect of tamoxifen and melatonin on mammary gland cancer induced by N-methyl-N-nitrosourea and by 7,12-dimethylbenz(a)-anthracene, respectively, in female Sprague–Dawley rats.
Folia Biol. 2001;47:5–10
- . Melatonin, a suppressor of spontaneous murine mammary tumors. J. Pineal Res. 1991;10:136–140
-
Melatonin increases both life span and tumor incidence in female CBA mice.
J. Gerontol. Biol. Sci. 2001;56A:B311–B323
- . Effect of melatonin on mammary gland lesions in transgenic mice overexpressing N-ras proto-oncogene. J. Pineal Res. 1997;22:86–94
-
.
Effect of melatonin and linoleic acid on mammary cancer in transgenic mice with c-neu breast cancer oncogene.
Breast Cancer Res. Treatm. 2000;64:287–296
- . Mammary carcinogenesis induced in Wistar:Han rats by the combination of ionizing radiation and dimethylbenz(a)anthracene: prevention with melatonin. Neoplasma. 2000;47:227–229
- . Effects of melatonin on N-nitroso-N-methylurea-induced carcinogenesis in rats and mutagenesis in vitro (Ames test and COMET assay). Cancer Lett. 1999;138:37–44
-
.
Differential effect of melatonin on early and advanced passages of a DMBA-induced mammary carcinoma in the female rat.
Adv. Pineal Res. 1994;7:247–252
- Modulation of cancer endocrine therapy by melatonin: a phase II study of tamoxifen plus melatonin in metastatic breast cancer patients progressing under tamoxifen alone. Br. J. Cancer. 1995;71:854–856
-
.
Efficacy of melatonin in the immunotherapy of cancer using interleukin-2.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 463–475
-
.
Melatonin cancer therapy.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 476–508
-
.
Effect of melatonin administration in advanced breast cancer patients—preliminary report.
Neuroendocrinol. Lett. 1998;19:15–19
-
.
Melatonin in clinical oncology.
Neroedocrinol. Lett. 2002;23(Suppl 1):30–38
-
.
Pineal melatonin synthesis and secretion during induction and growth of mammary cancer in female rats.
In:
Gupta D, Wollmann HA, Ranke MB editor. Neuroendocrinology: new frontiers. London and Tubingen: Brain Research Promotion; 1990;p. 326–332
-
.
Effect of the mammary carcinogen 7,12-dimethylbenz[a]anthracene on pineal melatonin biosynthesis, secretion and peripheral metabolism.
Neuronedocrinology. 1990;52:538–544
- . Hepatic hydroxylation of melatonin in the rat is induced by phenoobarbital and 7,12-dimethylbenz[a]anthracene-implications for cancer etiology. Experientia. 1995;51:349–355
-
.
The modulation of melatonin in tumor-bearing animals: underlying mechanisms and possible significance for prognosis.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 197–209
- . Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy. Curr. Top. Med. Chem. 2002;2:113–132
-
.
Light during darkness, melatonin suppression and cancer progression.
Neuroendocrinol. Lett. 2002;23(Suppl 2):52–56
-
.
Oncostatic action of melatonin: facts and question marks.
Neuroendocrinol. Lett. 2002;23(Suppl 1):24–29
-
.
The pineal and its hormones in the control of reproduction in mammals.
Endocrin. Rev. 1980;1:109–131
- Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology. 2000;141:487–497
-
.
Modulation of the estrogen response pathway in human breast cancer cells by melatonin.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 343–358
- Modulatory effects of melatonin on genotoxic response of reference mutagens in the Ames test and the comet assay. Mutat. Res. 1998;417:75–84
- . Melatonin reduces gamma radiation-induced primary DNA damage in human blood lymphocytes. Mutat. Res. 1998;397:203–208
-
.
Reactive oxygen species, DNA damage, and carcinogenesis: intervention with melatonin.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 442–455
- . Pathways through which a regimen of melatonin and retinoic acid induced apoptosis in MCF-7 human breast cancer cells. Breast Cancer Res. Treat. 2000;61:229–239
-
.
Antiangiogenic activity of melatonin in advanced cancer patients.
Neuroendocrinol. Lett. 2001;22:45–47
-
.
Potential anticarcinogenic action of melatonin and other antioxidants mediated by antioxidative mechanisms.
Neuroendocrinol. Lett. 2002;23(Suppl 1):39–44
- . Polysaturated fatty acids, melatonin, and cancer prevention. Biochem. Pharmacol. 2001;61:1455–1462
-
.
Melatonin and the immune system: therapeutic potential in cancer, viral diseases, and immunodeficiency states.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 384–394
-
.
Melatonin in immunity: comparative aspects.
Neurondocrinol. Lett. 2002;23(Suppl 1):61–66
- . Pineal indoles stimulate the gene expression of immunomodulating cytokines. J. Neural Transm. 2001;108:397–405
-
.
Study on the effect of melatonin on gene expression in mouse heart using microarray technology.
Dokl. Russ. Acad. Sci. 2002;383:276–281
- Involvement of the mt1 melatonin receptor in human breast cancer. Cancer Lett. 2002;179:141–150
- . Effect of exogenous melatonin on hepatic energetic status during ischemia/reperfusion: possible role of tumornecrosis factor-α and nitric oxide. J. Surg. Res. 2001;100:141–149
- . Evidence for a direct effect of melatonin on mitochondrial genome expression of Siberian hamster adipocytes. J. Pineal Res. 2001;30:108–115
- . Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. Cell Growth Differ. 1998;9:435–449
- . Proteolysis and the G1-S transition: the SCF connection. Curr. Opin. Genet. Dev. 1998;8:36–42
- . SCF and Cullin/Ring H2-based ubiquitin ligases. Annu. Rev. Cell Dev. Biol. 1999;15:435–467
- VACM-1, a cullin gene family member, regulates cellular signaling. Am. J. Physiol. Cell Physiol. 2000;279(1):C266–273
- . The molecular basis and clinical aspects of Peutz-Jeghers syndrome. Cell Mol. Life Sci. 1999;55(5):735–750
-
.
Studies on a non-melatonin pineal antiginadotropin.
Acta Endocrinol. 1972;69:257–266
-
.
Pineal peptides and reproduction.
In:
Relkin R editors. The pineal gland. Amsterdam: Elsevier; 1983;p. 201–224
- Partial purification of a low molecular weight ovine pineal compound(s) with an inhibiting effect on the growth of human melanoma cells in vitro. J. Neural Transm. 1988;73:135–155
- A cytotoxic, apoptotic, low-molecular weight factor from pineal gland. Life Sci. 1999;65:1047–1057
-
.
Serial transplants of DMBA-induced mammary tumours in Fischer rats as model system for human breast cancer: I. Effect of melatonin and pineal extracts on slow- and fast-growing passages—in vivo and in vitro studies.
Adv. Pineal Res. 1994;8:473–478
-
.
A survey of the evidence that melatonin and unidentified pineal substances affect neoplastic growth.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 275–293
-
.
Peptide Bioregulators (25-years Experience of Experimental and Clinical Study). St. Petersburg: Nauka; 1996;
-
.
Experimental studies of the pineal gland preparation epithalamin.
In:
Bartsch C, Bartsch H, Blask DE, Cardinali DP, Hrushesky WJM, Mecke D editor. The pineal gland and cancer. Neuroimmunoendocrine mechanisms in malignancy. Berlin: Springer; 2001;p. 294–306
- . Study on the anti-tumor effect of polypeptide pineal extract. Oncology. 1979;36:274–280
-
.
Effect of polypeptide pineal preparation on life span and spontaneous tumor incidence in old female rats.
Dokl. Akad. Nauk. USSR. 1991;319:250–254
- . Carcinogenesis and aging. IV. Effect of low-molecular weight factors of thymus, pineal gland and anterior hypothalamus on immunity, tumor incidence and life span of C3H/Sn mice. Mech. Ageing Dev. 1982;19:245–258
- . Effect of low-molecular-weight factors of thymus and pineal gland on life span and spontaneous tumour development in female of different age. Mech. Ageing Dev. 1989;49:245–257
-
.
Inhibition of carcinogenic effect of 7,12-dimethylbenz(a)anthracene with buformin, diphenylhydantoin, polypeptide pineal extract and l-DOPA in female rats.
Bull. Exp. Biol. Med. 1980;89:723–725
-
.
Effect of polypeptide factors of thymus and epiphysis on radiation carcinogenesis.
Bull. Exp. Biol. Med. 1982;94:26–29
-
.
Twenty years of study on effects of pineal peptide preparation: epithalamin in experimental gerontology and oncology.
Ann. N.Y. Acad. Sci. 1994;719:483–493
-
.
Pineal gland, immunity and cancer (Theoretical and clinical aspects). Tomsk: Tomsk University; 1990;
- . Effect of epithalon on lifespan increase in Drosophila melanogaster. Mech. Ageing Dev. 2000;120:141–149
-
.
Epitalon inhibits development of tumors and expression of HER-2/neu oncogene in mammary tumors in transgenic mice with accelerated aging.
Bull. Exp. Biol. Med. 2002;132:56–59
-
.
Effects of pineal peptide preparation Epithalamin on free radical processes in humans and animals.
Neuroendocrinol. Lett. 2001;22:11–20
-
.
Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in senescent monkeys.
Neuroendocrinol. Lett. 2001;22:251–254
-
.
Effect of pineal peptides on neuroendocrine system after pinealectomy.
Arkhiv. Pathol. 2001;63(3):18021
- . Reparative effect of epitalon on pineal ultrastructure in gamma-irradiated rats. Bull. Exp. Biol. Med. 2001;131:81–85
- . Effect of synthetic thymic and pineal peptides on biomarkers of ageing, survival and spontaneous tumour incidence in female CBA mice. Mech. Ageing Dev. 2001;122:41–68
-
Effect of Epitalon on chromosome lesion incidence in senescence accelerated (SAM) mice.
Bull. Exp. Biol. Med. 2002;133:320–322
-
.
Study on the effect of peptides Vilon and Epitalon on gene expression in mouse heart using microarray technology.
Bull. Exp. Biol. Med. 2002;133:340–347
- . Inhibitory effect of peptide Epitalon on colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. Cancer Lett. 2002;183:1–8
-
.
Does light cause internal cancers?—The problem and challenge of an ubiquitous exposure.
Neuroendocrinol. Lett. 2002;23(Suppl 2):61–70
-
.
The darkness at the end of the tunnel: summary and evaluation of an International Symposium on Light Endocrine Systems and Cancer.
Neuroendocrinol. Lett. 2002;23(Suppl 2):71–78
-
.
Light, endocrine systems and cancer—A meeting report.
Neuroendocrinol. Lett. 2002;23(Suppl 2):84–87
PII: S1040-8428(03)00021-0
doi: 10.1016/S1040-8428(03)00021-0
© 2003 Elsevier Science Ireland Ltd. All rights reserved.
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Critical Reviews in Oncology / Hematology
Volume 46, Issue 3
, Pages 221-234
, June 2003
