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Current issues in combined modality therapy in locally advanced head and neck cancer
17 May 2012
Anthony J. Cmelak
Abstract: Curative treatment for patients with locally advanced squamous cell carcinomas of the head and neck (SCCHN) is complex and multidisciplinary. Our understanding of the optimal management of t...
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Central nervous system chemotoxicity during treatment of pediatric acute lymphoblastic leukemia/lymphoma
14 May 2012
Jose Manuel Vagace, Maria Dolores de la Maya, Cristina Caceres-Marzal, Silvia Gonzalez de Murillo, Guillermo Gervasini
Abstract: In the last decades, increasing success rates are being obtained in the chemotherapy of pediatric leukemia and lymphoma. However, the cornerstone of this treatment is still formed by a reduc...
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Brain metastases from gastrointestinal tumours: Tailoring the approach to maximize the outcome
14 May 2012
Jessica Menis, Caterina Fontanella, Alessandro Follador, Gianpiero Fasola, Giuseppe Aprile
Abstract: Brain metastases from the gastrointestinal cancers (GI) are uncommon, but their incidence is constantly increasing due to several reasons, including improved systemic therapy and survival. N...
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Angiogenesis: A promising therapeutic target for ovarian cancer
10 May 2012
A. Bamias, S. Pignata, E. Pujade-Lauraine
Abstract: Ovarian cancer is the leading cause of death from gynecological cancers. Primary treatment of advanced ovarian cancer (FIGO stages III and IV) until recently consisted of cytoreductive surge...
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Cancer chemotherapy: A critical analysis of its 60 years of history
30 April 2012
Darío Galmarini, Carlos M. Galmarini, Felipe C. Galmarini
Abstract: Chemotherapy has already proven widely effective in the treatment of cancer, occupying a prominent place in the current therapeutic arsenal. However, in recent years, there has been a platea...
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